Book Review: When Breath Becomes Air
Author: Paul Kalanithi
Book Reviewer: McKenzie Mayer
When Breath Becomes Air is a memoir by Dr. Paul Kalanithi, a neurosurgeon diagnosed with terminal lung cancer at the peak of his medical career. The book captures his profound reflections on life, death, and what it means to live with purpose. Divided into two parts, the first describes his path to becoming a neurosurgeon. He details his academic journey, training, and the ethical complexities he faced in medicine. The second part begins with his diagnosis and follows his transition from doctor to patient. Dr. Kalanithi also discusses how he confronts the emotional, physical, and existential challenges of living while dying.
From the very beginning of the memoir, Dr. Kalanithi is guided by a deep desire to understand what makes life meaningful. He first seeks answers through literature and philosophy, earning a degree in English literature at Stanford. However, he ultimately turns to medicine, believing that true insight lies in confronting mortality firsthand. Becoming a physician gives him a new lens to explore suffering, meaning, and purpose through lived experience. However, his understanding of life is profoundly challenged when he is diagnosed with terminal lung cancer. Once a rising neurosurgeon nearing the end of a decade-long training journey, he is abruptly placed into the role of patient. A particularly powerful moment that captures this transformation occurs when he views his own CT scan and sees tumors scattered across his lungs. He describes the psychological split between his trained, clinical mind and the raw emotional response to seeing himself as the subject of the scan.
The fragility of time and the urgency of legacy also emerge as central themes in the latter half of the memoir. With his time suddenly limited, Dr. Kalanithi begins to reflect on how he wants to be remembered. Writing the memoir becomes not just a means of recording his story, but a final act of purpose—a way to contribute something lasting to the world. This desire to leave a legacy is also evident in his decision to have a child despite his terminal diagnosis. The birth of his daughter brings him renewed joy and meaning, even as he faces the end of his life. In his final months, he writes letters to her in hopes that his words will one day provide comfort, connection and guidance. Through both writing and fatherhood, Dr. Kalanithi leaves behind a legacy grounded in love, reflection and a genuine commitment to living with intention.
Lastly, the epilogue—written by Dr. Lucy Kalanithi—serves as a powerful and intimate eulogy. It allows readers to see Dr. Kalanithi not only through his own words, but also through the eyes of someone who loved him deeply. Their love story—beginning as medical students, deepening through marriage, and evolving through illness, parenthood, and Dr. Kalanithi’s final moments—serves as a poignant testament to their bond. Dr. Lucy Kalanithi recounts the emotional and physical toll of Dr. Kalanithi’s illness and his courageous decision to forgo intubation. He instead chose to die with dignity surrounded by loved ones, just as he would have wished for his own patients.
Reading this memoir deeply challenged my perspective as a young medical student, still learning how to make sense of life and death. Even though I’ve already witnessed death in various clinical settings, the concept still frightens me. Despite our proximity to suffering and mortality in medicine, many of us carry a quiet illusion that we are somehow exempt. We often view ourselves strictly as caregivers, never imagining we could so suddenly become the patient. When Breath Becomes Air shattered that illusion. Dr. Kalanithi’s story forced me to confront the truth that death is not reserved for the old, the frail, or the distant—it is something we will all eventually share, regardless of age or ambition.
What struck me most was not just Dr. Kalanithi’s illness, but the clarity and purpose with which he lived even in the face of dying. It made me reflect on the kind of doctor I aspire to be. Not just someone who diagnoses and treats, but someone who listens, empathizes, and sees the human being behind every patient. Dr. Kalanithi’s writing reminded me that the measure of a life isn’t in how long it lasts, but in how deeply and intentionally it is lived. This is the kind of presence I hope to bring to every patient encounter.
About the Author: Paul Kalanithi
Paul Sudhir Arul Kalanithi was a neurosurgeon and writer, best known for his deeply moving memoir When Breath Becomes Air. He wrote the book based on his life and his experience confronting a terminal diagnosis of stage IV metastatic lung cancer. He was diagnosed at age thirty-six during his sixth year of neurosurgery residency at Stanford, despite never having smoked.
Prior to becoming a physician, he studied at Stanford University and graduated in 2000 with a BA in English literature as well as a BS in human biology. He then received a master’s in the history and philosophy of science and medicine from the University of Cambridge. Afterwards, he went on to the Yale School of Medicine where he met his future wife, Lucy Goddard. He graduated in 2007 cum laude, winning the Lewis H. Nahum Prize for his research on Tourette’s syndrome before returning to Stanford for residency.
Kalanithi was fascinated with the intersection of science, philosophy, and mortality, often reflecting on what makes life meaningful from both a medical and humanistic standpoint. His memoir includes many of these themes, offering a touching meditation on purpose, belief, and what it means to truly live in the face of death.
About the Reviewer: McKenzie Mayer
McKenzie Mayer is a second-year medical student at Hackensack Meridian School of Medicine. She graduated with distinction from the University of Michigan, earning a Bachelor of Science in Biology, Health, and Society. Originally from Rockland County, NY, McKenzie’s interest in orthopaedic surgery began in high school when she was selected for the county’s competitive New Visions Health program. Through this program she was able to complete an internship with a sports medicine orthopaedic surgeon, which solidified her passion for the field.
A former competitive cheerleader of 15 years, McKenzie stays connected to the sport by volunteering with Project Cheerup!, a national nonprofit dedicated to spreading joy through cheerleader-led philanthropic efforts. In her free time, McKenzie also enjoys photography, cooking, exploring new restaurants, traveling, and spending time with family and friends.
This year, she serves as the Associate Resource Development Coordinator for the Association of Women Surgeons (AWS) National Medical Student Committee, where she is helping to expand and develop the committee’s podcast, Knots & Thoughts.

